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Nigeria defeated Ghana 2-1 in a friendly played in Marrakech, Morocco, on Friday evening.
The Finidi George led Eagles failed to convert more chances in the game.
The two West African rivals took advantage of the FIFA international break to face each other.
The Super Eagles dominated early proceedings and took the lead through Cyril Dessers who stroked home the ball from the penalty spot in the 38th minute.
However, in the second half, Alex Iwobi found Ademola Lookman in the box and he lashed home an emphatic second, while fo Jordan Ayew to pull one back in the closing stage for the black stars.
The Eagles will face Mali in another friendly in four days.